Please use this identifier to cite or link to this item: http://dspace.ltsu.org//handle/123456789/2439
Title: Novel Method of 4,6-Dimethyl-2-thioxo-1,2-dihydronicotinonitrile Synthesis.
Authors: Dyachenko, I. V.
Keywords: acetaldehyde
cyanothioacetamide
1-(prop-1-en-2-yl)pyrrolidine
2-thioxo-1,2-dihydronicotinonitrile
2-alkylsulfanylnicotinonitriles
thieno[2,3-b]pyridines
Issue Date: 19-Mar-2018
Abstract: Condensation of acetaldehyde with cyanothioacetamide and 1-(prop-1-en-2-yl)pyrrolidine has afforded 4,6-dimethyl-2-thioxo-1,2-dihydronicotinonitrile. Alkylation of the latter with α-haloketones yields substituted 2-alkylsulfanyl-4,6-dimethylnicotinonitriles and thieno[2,3-b]pyridines.
URI: http://dspace.ltsu.org//handle/123456789/2439
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